《Nature》目录：2010-06-17出版
时间：2010-06-18 阅读： 我要评论:
disease.
Liping Zhao
doi:10.1038/465879a
http://www.nature.com/nature/journal/v465/n7300/full/465879a.html
Condensed-matter physics: Single skyrmions spotted pp880-881
Skyrmions are a special type of particle that has long been predicted to
exist in many fields of physics. Direct images of these structures have now
been made in a magnetic material.
Christian Pfleiderer and Achim Rosch
doi:10.1038/465880a
http://www.nature.com/nature/journal/v465/n7300/full/465880a.html
Conservation biology: When an infection turns lethal pp881-882
Losses in biodiversity and the emergence of new infectious diseases are
among the greatest threats to life on the planet. The declines in amphibian
populations lie at the interface between these issues.
Andrew R. Blaustein and Pieter T. J. Johnson
doi:10.1038/465881a
http://www.nature.com/nature/journal/v465/n7300/full/465881a.html
Structural biology: Immunity takes a heavy Toll pp882-883
Toll receptors trigger immune responses through adaptor proteins and kinase
enzymes. Structural studies reveal that hierarchical assembly of these
proteins into a helical tower initiates downstream signalling events.
Steven A. Wasserman
doi:10.1038/465882a
http://www.nature.com/nature/journal/v465/n7300/full/465882a.html
Obituary: Martin Gardner (1914-2010) p884
'Mathemagician' who popularized maths and debunked pseudoscience.
David Singmaster
doi:10.1038/465884a
http://www.nature.com/nature/journal/v465/n7300/full/465884a.html
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ARTICLES
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Helical assembly in the MyD88--IRAK4--IRAK2 complex in TLR/IL-1R
signalling pp885-890
Toll-like receptors (TLRs) are crucial to innate immunity. Activation of
these proteins, and of receptors for the pro-inflammatory cytokines IL-1 and
IL-18, leads to the recruitment of adaptor proteins such as MyD88. These in
turn interact with further proteins such as IRAK2 and IRAK4. The crystal
structure of the MyD88-IRAK2-IRAK4 death domain complex is now reported,
explaining how these three proteins cooperate in TLR/IL-1R signalling.
Su-Chang Lin, Yu-Chih Lo and Hao Wu
doi:10.1038/nature09121
Abstract:
http://www.nature.com/nature/journal/v465/n7300/abs/nature09121.html
Article:
http://www.nature.com/nature/journal/v465/n7300/full/nature09121.html
| 《Nature》目录要览 — 2011-04-28出版 |
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