《Nature》目录要览 — 2011-04-28出版

[自然要览]

（选自英国Nature杂志，2011年4月28日出版）

海马神经生成与认知功能之间的关系
http://www.natureasia.com/ch/nature/updates/index.php?i=82693&issue=7344

封面故事: “噬菌细胞”检测入侵微生物的机制
http://www.natureasia.com/ch/nature/updates/index.php?i=82695&issue=7344

线粒体在先天免疫中的作用
http://www.natureasia.com/ch/nature/updates/index.php?i=82697&issue=7344

RORγt的一组抑制因子
http://www.natureasia.com/ch/nature/updates/index.php?i=82701&issue=7344

生成有用生物分子的快速方法
http://www.natureasia.com/ch/nature/updates/index.php?i=82707&issue=7344

“Agulhas洋流”的作用
http://www.natureasia.com/ch/nature/updates/index.php?i=82715&issue=7344

与自闭症有关的蛋白
http://www.natureasia.com/ch/nature/updates/index.php?i=82717&issue=7344

半梦半醒之间
http://www.natureasia.com/ch/nature/updates/index.php?i=82719&issue=7344

ISW1a和核小体的相互作用
http://www.natureasia.com/ch/nature/updates/index.php?i=82721&issue=7344

宇宙中的“第一批恒星”
http://www.natureasia.com/ch/nature/updates/index.php?i=82723&issue=7344

超导性的转变
http://www.natureasia.com/ch/nature/updates/index.php?i=82725&issue=7344
 

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NEWS & VIEWS
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Earth science: Lithosphere today ... pp420 - 421
Seismic images of the Colorado plateau region reveal a mantle 'drip' forming under the Grand Canyon area. This hidden process may be responsible for the puzzling uplift of the plateau. See Letter p.461
George Zandt and Peter Reiners
doi:10.1038/472420a
Article: http://www.nature.com/nature/journal/v472/n7344/full/472420a.html

Immunology: A helping hand against autoimmunity pp421 - 422
The TH17 helper cells of the immune system have a dark side: they mediate autoimmune disorders. Two drugs that prevent the differentiation and activity of these cells might be of therapeutic value. See Letters p.486 & p.491
Anton M. Jetten
doi:10.1038/472421a
Article: http://www.nature.com/nature/journal/v472/n7344/full/472421a.html

50 & 100 years ago p422
doi:10.1038/472422a
Article: http://www.nature.com/nature/journal/v472/n7344/full/472422a.html

Materials science: Colour without colourants pp423 - 424
Creating coloured polymer films without the use of pigments might seem impossible. But using miniature polymer spheres, and a novel assembly process, this feat has been accomplished over large film areas.
Paul V. Braun
doi:10.1038/472423a
Article: http://www.nature.com/nature/journal/v472/n7344/full/472423a.html

Animal behaviour: Large-scale cooperation pp424 - 425
A deeper understanding of the evolution of cooperation will come from investigations of what animals know about working together. A study with Asian elephants now adds to the literature on the subject.
Amanda M. Seed and Keith Jensen
doi:10.1038/472424a
Article: http://www.nature.com/nature/journal/v472/n7344/full/472424a.html

Materials chemistry: Polymer networks take a bow pp425 - 426
A new study reports that the shapes and surface patterns of thin films of a stretched material can be modified by shining ultraviolet light at it. The resulting topologies depend on the exposure pattern, the applied stress and the sample thickness.
Wilhelm T. S. Huck
doi:10.1038/472425a
Article: http://www.nature.com/nature/journal/v472/n7344/full/472425a.html

Astronomy: A new spin on the first stars pp426 - 427
Understanding the nature of the first stars, whose formation marked a pivotal epoch in the Universe's history, is at the frontier of astronomy. An analysis of stellar data indicates that they were fast-rotating objects. See Letter p.454
Jason Tumlinson
doi:10.1038/472426a
Article: http://www.nature.com/nature/journal/v472/n7344/full/472426a.html

Neuroscience: Sleepy neurons? pp427 - 428
A study in rats suggests that individual neurons take a nap when the brain is forced to stay awake, and that the basic unit of sleep is the electrical activity of single cortical neurons. See Article p.443
Christopher S. Colwell
doi:10.1038/472427a
Article: http://www.nature.com/nature/journal/v472/n7344/full/472427a.html

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REVIEW
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On the role of the Agulhas system in ocean circulation and climate pp429 - 436
Lisa M. Beal et al.
doi:10.1038/nature09983
Abstract: http://www.nature.com/nature/journal/v472/n7344/abs/nature09983.html
Article: http://www.nature.com/nature/journal/v472/n7344/full/nature09983.html

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ARTICLES
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Shank3 mutant mice display autistic-like behaviours and striatal dysfunction pp437 - 442
Joao Peca et al.
doi:10.1038/nature09965
Abstract: http://www.nature.com/nature/journal/v472/n7344/abs/nature09965.html
Article: http://www.nature.com/nature/journal/v472/n7344/full/nature09965.html

Local sleep in awake rats pp443 - 447
Vladyslav V. Vyazovskiy et al.
doi:10.1038/nature10009
Abstract: http://www.nature.com/nature/journal/v472/n7344/abs/nature10009.html
Article: http://www.nature.com/nature/journal/v472/n7344/full/nature10009.html

Structure and mechanism of the chromatin remodelling factor ISW1a pp448 - 453
Kazuhiro Yamada et al.
doi:10.1038/nature09947
Abstract: http://www.nature.com/nature/journal/v472/n7344/abs/nature09947.html
Article: http://www.nature.com/nature/journal/v472/n7344/full/nature09947.html

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LETTERS
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Imprints of fast-rotating massive stars in the Galactic Bulge pp454 - 457
Cristina Chiappini et al.
doi:10.1038/nature10000
Abstract: http://www.nature.com/nature/journal/v472/n7344/abs/nature10000.html
Article: http://www.nature.com/nature/journal/v472/n7344/full/nature10000.html

Superconductor–insulator transition in La2 − xSrxCuO4 at the pair quantum resistance pp458 - 460
A. T. Bollinger et al.
doi:10.1038/nature09998
Abstract: http://www.nature.com/nature/journal/v472/n7344/abs/nature09998.html
Article: http://www.nature.com/nature/journal/v472/n7344/full/nature09998.html

Continuing Colorado plateau uplift by delamination-style convective lithospheric downwelling pp461 - 465
A. Levander et al.
doi:10.1038/nature10001
Abstract: http://www.nature.com/nature/journal/v472/n7344/abs/nature10001.html
Article: http://www.nature.com/nature/journal/v472/n7344/full/nature10001.html

Increasing adult hippocampal neurogenesis is sufficient to improve pattern separation pp466 - 470
Amar Sahay et al.
doi:10.1038/nature09817
Abstract: http://www.nature.com/nature/journal/v472/n7344/abs/nature09817.html
Article: http://www.nature.com/nature/journal/v472/n7344/full/nature09817.html

Activation of the innate immune receptor Dectin-1 upon formation of a ‘phagocytic synapse’ pp471 - 475
Helen S. Goodridge et al.
doi:10.1038/nature10071
Abstract: http://www.nature.com/nature/journal/v472/n7344/abs/nature10071.html
Article: http://www.nature.com/nature/journal/v472/n7344/full/nature10071.html

TLR signalling augments macrophage bactericidal activity through mitochondrial ROS pp476 - 480
A. Phillip West et al.
doi:10.1038/nature09973
Abstract: http://www.nature.com/nature/journal/v472/n7344/abs/nature09973.html
Article: http://www.nature.com/nature/journal/v472/n7344/full/nature09973.html

A diverse range of gene products are effectors of the type I interferon antiviral response pp481 - 485
John W. Schoggins et al.
doi:10.1038/nature09907
Abstract: http://www.nature.com/nature/journal/v472/n7344/abs/nature09907.html
Article: http://www.nature.com/nature/journal/v472/n7344/full/nature09907.html

Digoxin and its derivatives suppress TH17 cell differentiation by antagonizing RORγt activity pp486 - 490
Jun R. Huh et al.
doi:10.1038/nature09978
Abstract: http://www.nature.com/nature/journal/v472/n7344/abs/nature09978.html
Article: http://www.nature.com/nature/journal/v472/n7344/full/nature09978.html

Suppression of TH17 differentiation and autoimmunity by a synthetic ROR ligand pp491 - 494
Laura A. Solt et al.
doi:10.1038/nature10075
Abstract: http://www.nature.com/nature/journal/v472/n7344/abs/nature10075.html
Article: http://www.nature.com/nature/journal/v472/n7344/full/nature10075.html

Differential microRNA regulation of HLA-C expression and its association with HIV control pp495 - 498
Smita Kulkarni et al.
doi:10.1038/nature09914
Abstract: http://www.nature.com/nature/journal/v472/n7344/abs/nature09914.html
Article: http://www.nature.com/nature/journal/v472/n7344/full/nature09914.html

A system for the continuous directed evolution of biomolecules pp499 - 503
Kevin M. Esvelt, Jacob C. Carlson and David R. Liu
doi:10.1038/nature09929
Abstract: http://www.nature.com/nature/journal/v472/n7344/abs/nature09929.html
Article: http://www.nature.com/nature/journal/v472/n7344/full/nature09929.html
 

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