英国《Nature》：2010年3月25日出版
时间：2010-03-26 阅读： 我要评论:
doi:10.1038/nature08930
Abstract:
http://www.nature.com/nature/journal/v464/n7288/abs/nature08930.html
Article:
http://www.nature.com/nature/journal/v464/n7288/full/nature08930.html
A computational model of teeth and the developmental origins of
morphological
variation pp583-586
Genotype and phenotype cannot be connected simply by one-to-one mapping;
instead
they are linked by the nonlinear process of development. Here, a
computational
model is described - based on real data about the development of seal teeth
-
that attempts to combine the three. The results show that a few genetic
parameters
regulating signalling during cusp development may explain variation among
individuals. But a cellular parameter regulating epithelial growth may
explain
tooth-to-tooth variation along the jaw.
Isaac Salazar-Ciudad and Jukka Jernvall
doi:10.1038/nature08838
Abstract:
http://www.nature.com/nature/journal/v464/n7288/abs/nature08838.html
Article:
http://www.nature.com/nature/journal/v464/n7288/full/nature08838.html
Whole-genome resequencing reveals loci under selection during chicken
domestication
pp587-591
Here, the genomes of birds representing eight populations of domestic
chickens
are compared with the genome of their wild ancestor, the red jungle fowl.
The
results reveal selective sweeps of favourable alleles and mutations that may
have contributed to domestication. One selective sweep, for instance,
occurred
at the locus encoding the thyroid stimulating hormone receptor, which is
important in metabolism and in the timing of vertebrate reproduction.
Carl-Johan Rubin et al.
doi:10.1038/nature08832
Abstract:
http://www.nature.com/nature/journal/v464/n7288/abs/nature08832.html
Article:
http://www.nature.com/nature/journal/v464/n7288/full/nature08832.html
The dynamic genome of Hydra pp592-596
The freshwater cnidarian Hydra is a significant model for studies of axial
patterning, stem cell biology and regeneration. Its (A+T)-rich genome has
now
been sequenced. Comparison of this genome with those of other animals
provides
insights into the evolution of epithelia, contractile tissues,
developmentally
regulated transcription factors, pluripotency genes and more.
Jarrod A. Chapman et al.
doi:10.1038/nature08830
Abstract:
http://www.nature.com/nature/journal/v464/n7288/abs/nature08830.html
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