英国《Nature》：2010年3月25日出版
时间：2010-03-26 阅读： 我要评论:
http://www.nature.com/nature/journal/vaop/ncurrent/full/nature08956.html
14 February 2010
Neurogenic radial glia in the outer subventricular zone of human neocortex
In the mammalian brain, the subventricular zone (SVZ) produces neural
progenitor cells that migrate into the cortex to populate the upper layers.
In humans this region is massively expanded, producing an outer SVZ (OSVZ).
Here, live-cell imaging of developing human tissue was used to show that the
OSVZ has similar characteristics to the SVZ, with progenitor cells
proliferating in a way that depends on the Notch protein. The findings have
implications for our understanding of how the complex human brain evolved.
David V. Hansen, Jan H. Lui, Philip R. L. Parker and Arnold R. Kriegstein
doi:10.1038/nature08845
Abstract:
http://www.nature.com/nature/journal/vaop/ncurrent/full/nature08845.html
Article:
http://www.nature.com/nature/journal/vaop/ncurrent/full/nature08845.html
14 February 2010
Neurogenic radial glia in the outer subventricular zone of human neocortex
In the mammalian brain, the subventricular zone (SVZ) produces neural
progenitor cells that migrate into the cortex to populate the upper layers.
In humans this region is massively expanded, producing an outer SVZ (OSVZ).
Here, live-cell imaging of developing human tissue was used to show that the
OSVZ has similar characteristics to the SVZ, with progenitor cells
proliferating in a way that depends on the Notch protein. The findings have
implications for our understanding of how the complex human brain evolved.
David V. Hansen, Jan H. Lui, Philip R. L. Parker and Arnold R. Kriegstein
doi:10.1038/nature08845
Abstract:
http://www.nature.com/nature/journal/vaop/ncurrent/full/nature08845.html
Article:
http://www.nature.com/nature/journal/vaop/ncurrent/full/nature08845.html
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