《Nature》目录要览:2010-12-23出版

时间:2010-12-24  阅读:    我要评论:

http://www.nature.com/nature/journal/v468/n7327/full/4681044a.html

Quantum technology: Electrons spin in the field pp1045 - 1046
Nanowires are candidates for enabling the exchange of quantum  information between light and matter. The rapid control of a single  electron spin by solely electrical means brings this possibility  closer. See Letterp.1084
David J. Reilly
doi:10.1038/4681045a
Article: http://www.nature.com/nature/journal/v468/n7327/full/4681045a.html

Structural biology: Proteins in dynamic equilibrium pp1046 - 1048
Protein molecules in solution exist as an equilibrium of different  conformations, but the sizes and shifts of these populations cannot be  determined from static structures. A report now shows how they can be  measured in solution.
Pau Bernadó and Martin Blackledge
doi:10.1038/4681046a
Article: http://www.nature.com/nature/journal/v468/n7327/full/4681046a.html

Extrasolar planets: A giant surprise pp1048 - 1049
The discovery of an inner giant planet in the unusually massive solar  system around the star HR 8799 creates an ensemble of planets that is  difficult to explain with prevailing theories of planet formation. See  Letterp.1080
Laird Close
doi:10.1038/nature09716
Article: http://www.nature.com/nature/journal/v468/n7327/full/nature09716.html

Behavioural neuroscience: A gene for impulsivity pp1049 - 1050
Impulsivity has been linked to various psychiatric disorders and forms  of violent behaviour. A gene mutated in a population of violent  Finnish criminal offenders provides clues to the neural basis of this  trait. See articlep.1061
John R. Kelsoe
doi:10.1038/4681049a
Article: http://www.nature.com/nature/journal/v468/n7327/full/4681049a.html

Drug discovery: Reader's block pp1050 - 1051
Protein factors can regulate gene expression by binding to  specifically modified DNA-associated proteins. Small molecules that  selectively interfere with such interaction may be of therapeutic  value. See Articlep.1067 & Letterp.1119
Sean D. Taverna and PhiliP A. Cole
doi:10.1038/4681050a
Article: http://www.nature.com/nature/journal/v468/n7327/full/4681050a.html

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Genetic history of an archaic hominin group from Denisova Cave in  Siberia pp1053 - 1060
Using DNA from a finger bone, the genome of an archaic hominin from  southern Siberia has been sequenced to about 1.9-fold coverage. The  group to which this individual belonged shares a common origin with  Neanderthals, and although it was not involved in the putative gene  flow from Neanderthals into Eurasians, it contributed 4–6% of its  genetic material to the genomes of present-day Melanesians. A tooth  whose mitochondrial genome is very similar to that of the finger bone  further suggests that these hominins are evolutionarily distinct from  Neanderthals and modern humans.
David Reich et al.
doi:10.1038/nature09710
Abstract: http://www.nature.com/nature/journal/v468/n7327/abs/nature09710.html
Article: http://www.nature.com/nature/journal/v468/n7327/full/nature09710.html

A population-specific HTR2B stop codon predisposes to severe  impulsivity pp1061 - 1066
Impulsive behaviour characterizes several psychiatric diseases and  violent behaviour but its origins are complex. Here, exon sequencing  focused on fourteen serotonin- and dopamine-related genes identified a  mutation in HTR2B, which was associated with psychiatric diseases  marked by impulsivity in a Finnish population. The role of this  serotonin receptor in impulsivity is further supported by the knockout  mouse phenotype.
Laura Bevilacqua et al.
doi:10.1038/nature09629
Abstract: http://www.nature.com/nature/journal/v468/n7327/abs/nature09629.html
Article: http://www.nature.com/nature/journal/v468/n7327/full/nature09629.html

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