《Nature》目录要览：2010-12-02出版
时间：2010-12-02 阅读： 我要评论:
Neuroscience: Sexy circuits pp638 - 640
As in humans, the actions and reactions of male and female fruitflies during courtship are quite distinct. The differences seem to lie in gender-specific neural interpretations of the same sensory signals. See Letter p.686
Richard Benton
doi:10.1038/468638a
Article: http://www.nature.com/nature/journal/v468/n7324/full/468638a.html
50 & 100 years ago p639
doi:10.1038/468639a
Article: http://www.nature.com/nature/journal/v468/n7324/full/468639a.html
Analytical biochemistry: Weighing up protein folding pp640 - 641
Labelling molecules by fast oxidation allows mass spectrometry to study protein folding at submillisecond time resolution. The method also brings a wealth of structural information about protein folding within reach.
Martin Gruebele
doi:10.1038/468640a
Article: http://www.nature.com/nature/journal/v468/n7324/full/468640a.html
Parasitology: Nematode debt to bacteria pp641 - 642
The transition by certain nematode worms to plant parasitism, and possibly more generally to herbivory, is illuminated by an investigation into how nematodes acquired the protein weapons to penetrate the plant cell wall.
Noah K. Whiteman and Andrew D. Gloss
doi:10.1038/468641a
Article: http://www.nature.com/nature/journal/v468/n7324/full/468641a.html
High-temperature superconductivity: How the cuprates hid their stripes pp643 - 644
Extensive mapping of local electronic structure in copper oxide superconductors reveals fluctuating stripe-like electron patterns that appear as a high-temperature precursor to superconductivity. See Letter p.677
Kathryn A. Moler
doi:10.1038/468643a
Article: http://www.nature.com/nature/journal/v468/n7324/full/468643a.html
Stem cells: The blood balance pp644 - 645
Blood cells are generated from haematopoietic stem cells on demand. The protein Lkb1, which lies at the crossroad of energy metabolism and cell growth, seems to regulate these stem cells' dynamics. See Articles p.653, p.659 & Letter p.701
Ellen M. Durand and Leonard I. Zon
doi:10.1038/468644a
Article: http://www.nature.com/nature/journal/v468/n7324/full/468644a.html
Structural biology: An alphavirus puzzle solved pp645 - 646
Alphaviruses infect their host by binding to cellular receptors and fusing with cell membranes. New studies define the receptor-binding protein of these viruses and its regulation of the membrane-fusion reaction. See Letters p.705 & p.709
Margaret Kielian
doi:10.1038/468645a
Article: http://www.nature.com/nature/journal/v468/n7324/full/468645a.html
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REVIEW
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Impacts of biodiversity on the emergence and transmission of infectious diseases pp647 - 652
Felicia Keesing et al.
doi:10.1038/nature09575
Abstract: http://www.nature.com/nature/journal/v468/n7324/abs/nature09575.html
Article: http://www.nature.com/nature/journal/v468/n7324/full/nature09575.html
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ARTICLES
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Lkb1 regulates cell cycle and energy metabolism in haematopoietic stem cells pp653 - 658
Haematopoietic stem cells (HSCs) are very sensitive to energetic and oxidative stress, and modulation of the balance between their quiescence and proliferation is needed to respond to metabolic stress while preserving HSCs' long-term regenerative capacity. Here the tumour suppressor Lkb1 is shown to promote stem-cell maintenance and tissue regeneration by regulating energy metabolism and by preventing aneuploidy.
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