《Nature》目录要览：2010-12-16出版
时间：2010-12-16 阅读： 我要评论:
Francesco Stellacci and Andreas Mortensen
doi:10.1038/468906a
Article: http://www.nature.com/nature/journal/v468/n7326/full/468906a.html
Neuroscience: Angelman syndrome connections pp907 - 908
Neuronal networks in the brain that develop early in life underlie our ability to learn, remember and communicate. Genetic defects that perturb the fine-tuning of such neuronal connectivity can cause disease.
Peter Scheiffele and Asim A. Beg
doi:10.1038/468907a
Article: http://www.nature.com/nature/journal/v468/n7326/full/468907a.html
Physical chemistry: Model's reputation restored pp908 - 909
The structure of a mineral has been validated, ending the controversy about its potential usefulness as a model of an unusual magnetic lattice. This model might provide insight into superconductivity.
Mark A. de Vries and Andrew Harrison
doi:10.1038/468908a
Article: http://www.nature.com/nature/journal/v468/n7326/full/468908a.html
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REVIEW
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Emerging properties of animal gene regulatory networks pp911 - 920
Eric H. Davidson
doi:10.1038/nature09645
Article: http://www.nature.com/nature/journal/v468/n7326/full/nature09645.html
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ARTICLES
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Light-avoidance-mediating photoreceptors tile the Drosophila larval body wall pp921 - 926
Light sensing outside the eyes is common in many animals but is usually confined to specialized organs. Here, the entire body wall of the fruitfly larva is found to be tiled with blue- and ultraviolet- light sensing neuronal dendrites, which are essential for the larva's innate light-avoidance behaviour. The phototransduction machinery used by these neurons is distinct from other Drosophila photoreceptor molecules but similar to a system recently identified in nematode neurons.
Yang Xiang et al.
doi:10.1038/nature09576
Abstract: http://www.nature.com/nature/journal/v468/n7326/abs/nature09576.html
Article: http://www.nature.com/nature/journal/v468/n7326/full/nature09576.html
TRIM24 links a non-canonical histone signature to breast cancer pp927 - 932
A crystal structure of the tandem PHD and bromodomain regions of the transcription and chromatin regulator TRIM24 reveals combinatorial recognition of dual marks on the histone H3 tail. TRIM24 is involved in activation of oestrogen-dependent genes and is aberrantly expressed in breast cancer.
Wen-Wei Tsai et al.
doi:10.1038/nature09542
Abstract: http://www.nature.com/nature/journal/v468/n7326/abs/nature09542.html
Article: http://www.nature.com/nature/journal/v468/n7326/full/nature09542.html
CRTC3 links catecholamine signalling to energy balance pp933 - 939
β-adrenergic receptor signalling in adipocytes stimulates energy expenditure via cAMP-dependent increases in lipolysis and fatty-acid oxidation, and this signalling mechanism is thought to be disrupted in obesity. Here, the cAMP-responsive CREB coactivator Crtc3 is shown to promote obesity in mice by attenuating β adrenergic receptor signalling in adipose tissue.
Youngsup Song et al.
doi:10.1038/nature09564
Abstract: http://www.nature.com/nature/journal/v468/n7326/abs/nature09564.html
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